Table 1. Structural organisation and intracellular localisation of individual members of the HDAC classes.

HDAC class	HDAC name	Domain organisation	Cellular localisation
Class I	HDAC1		Nucleus/Axon
Class I	HDAC2		Nucleus
Class I	HDAC3		Nucleus/Axon
Class I	HDAC8		Nucleus/Cytoplasm
Class IIa	HDAC4		Nucleus/Axon
Class IIa	HDAC5		Nucleus/Axon
Class IIa	HDAC7		Nucleus/Cytoplasm
Class IIa	HDAC9		Nucleus/Cytoplasm
Class IIb	HDAC6		Nucleus/Axon
Class IIb	HDAC10		Nucleus/Cytoplasm
Class III	SIRTS		Nucleus/Cytoplasm/Mitochondria
Class IV	HDAC11		Nucleus

Deacetylase domain, ZnF-UBP domain, MEF binding domain, Leucine rich-domain, SIRT deacetylase domain