Table 3.

Comparison of response levels and histopathological parameters between patients without KRAS mutation and those with a mutation on either codons 12, 13, 61 or 146.

Parameter	Level	KRAS mutation										p
		No (n = 49a)		Codon 12 (n = 29)		Codon 13 (n = 10)		Codon 61 (n = 3)		Codon 146 (n = 3)
		n	%	n	%	n	%	n	%	n	%
TRG	0	0	0	0	0	0	0	1	33	0	0	0.22
	1	4	8	6	21	0	0	1	33	1	33
	2	18	38	10	34	2	20	0	0	0	0
	3	20	42	11	38	6	60	0	0	1	33
	4	6	12	2	7	2	20	1	33	1	33
T-level downsizing (uT-yT)	0	20	41	18	62	2	20	1	33	2	67	0.14
	1	29	59	11	38	8	80	2	67	1	33
UICC downstaging (uUICC-yUICC)	0	24	49	10	34	1	10	0	0	2	67	0.07
	1	25	51	19	66	9	90	3	100	1	33
ypT	0	7	14	2	7	2	20	1	33	1	33	0.19
	1	8	16	2	7	2	20	1	33	0	0
	2	13	27	7	24	4	40	0	0	0	0
	3	18	37	16	55	2	20	0	0	1	33
	4	3	6	2	7	0	0	1	33	1	33
ypN	0	28	57	22	76	9	90	3	100	1	33	0.81
	1	14	29	6	21	1	10	0	0	2	67
	2	7	14	1	3	0	0	0	0	0	0

^aFor one patient TRG was not assessable.