Table 2.
Treatment patterns of nivolumab by age group
All patients (n=901) |
<75 years (n=723) |
≥75 years (n=178) |
Difference <75 years vs ≥75 years |
|
Treatment line, n (%) | ||||
Median (range) | 2.0 (1.0–12.0) | 3.0 (1.0–12.0) | 2.0 (1.0–9.0) | |
1 | 38 (4.2) | 33 (4.6) | 5 (2.8) | 0.0666*† |
2 | 422 (46.8) | 323 (44.7) | 99 (55.6) | |
3 | 239 (26.5) | 201 (27.8) | 38 (21.3) | |
≥4 | 202 (22.4) | 166 (23.0) | 36 (20.2) | |
Number of doses, median (range) | 5.0 (1.0–44.0) | 5.0 (1.0–44.0) | 5.0 (1.0–43.0) | 0.5074† |
Treatment duration, median (range) | 59.0 (1.0–693.0) | 59.0 (1.0–693.0) | 70.5 (1.0–602.0) | 0.4974† |
Patients who continued nivolumab after the study, n (%) | 129 (14.3) | 101 (14.0) | 28 (15.7) | 0.5511* |
*Fisher’s exact test.
†1 vs 2 vs 3 vs ≥4.