Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 20;8(2):e000772. doi: 10.1136/jitc-2020-000772

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

DC vaccination is able to reduce hallmarks of T-cell exhaustion. (A) Heatmap illustrating the average transcript expression of the indicated genes, grouped by function. Rows represent averaged z-scores. (B) Number and percentage of PD-1+, Tim-3+, VISTA+, CD39+ and NKG2A+ subsets of CD8 +TILs. (C) Number and percentage of IFNγ+, granzyme B+, IL-10+ and Ki67+ subsets of CD8 +TILs. n=7–8 per group. Significance was determined using the non-parametric Mann-Whitney U test. Data presented as the mean±SEM. *P<0.05, **P<0.01 DC, dendritic cell; IFNγ, interferon-γ; TILs, tumor infiltrating lymphocytes.