Table 3.
Diagnostic Value of Individual Colposcopic Findings in Predicting Vaginal Pathology at Different Cutoffs
| Colposcopic Findings and Cutoffs | Compared with Vaginal Histopathology | ||||
|---|---|---|---|---|---|
| Sensitivity | Specificity | PPV | NPV | YI | |
| Thin AWE | |||||
| LSIL+ | 75.86% | 37.20% | 41.77% | 72.19% | 0.1306 |
| HSIL+ | 23.81% | 30.27% | 1.58% | 89.40% | −0.4592 |
| Fine mosaic | |||||
| LSIL+ | 13.22% | 95.56% | 63.89% | 64.97% | 0.0878 |
| HSIL+ | 9.52% | 92.38% | 5.56% | 95.59% | 0.0190 |
| Fine punctuation | |||||
| LSIL+ | 20.69% | 94.88% | 70.59% | 66.83% | 0.1557 |
| HSIL+ | 9.52% | 89.01% | 3.92% | 95.43% | −0.0147 |
| Dense AWE | |||||
| LSIL+ | 12.64% | 97.95% | 78.57% | 65.38% | 0.1059 |
| HSIL+ | 57.17% | 96.41% | 42.86% | 97.95% | 0.5355 |
| Coarse mosaic | |||||
| LSIL+ | 1.15% | 99.66% | 66.67% | 62.93% | 0.0081 |
| HSIL+ | 9.52% | 99.78% | 66.67% | 95.91% | 0.0930 |
| Coarse punctuation | |||||
| LSIL+ | 1.72% | 98.63% | 42.86% | 62.83% | 0.0035 |
| HSIL+ | 14.29% | 99.10% | 42.86% | 96.09% | 0.1339 |
| Iodine negativity | |||||
| LSIL+ | 96.55% | 10.92% | 39.16% | 84.21% | 0.0747 |
| HSIL+ | 95.24% | 8.30% | 4.66% | 97.37% | 0.0354 |
| Erosion | |||||
| LSIL+ | 4.02% | 88.05% | 16.67% | 60.71% | −0.0793 |
| HSIL+ | 0 | 90.58% | 0 | 95.06% | −0.0942 |
Abbreviations: AWE, acetowhite epithelium; PPV, positive predictive value; NPV, negative predictive value; YI, Youden Index; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion.