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. 2020 Jul 22;252:490–501. doi: 10.1016/j.ejogrb.2020.07.034

Table 2.

Symptoms and treatments profile.

Meta-analysis of case series studies
Descriptive data analysis of case reports
Outcomes Meta-analysis
Individual data analysis
N I2 P(%) 95 %CI P(%)
Maternal signs and symptoms
Fever 26 83.67 % 0.58 0.48 0.67 0.64
Cough 26 85.49 % 0.52 0.42 0.62 0.60
Lymphopenia 18 91.40 % 0.46 0.31 0.62 0.38
Asymptomatic 20 84.94 % 0.09 0.02 0.19 0.09
Dyspnea 25 89.11 % 0.17 0.09 0.28 0.36
Fatigue 21 77.16 % 0.06 0.01 0.12 0.16
Diarrhea 23 48.86 % 0.03 0.01 0.06 0.04
Sore throat 22 66.57 % 0.03 0.01 0.08 0.22
Myalgia 21 83.25 % 0.06 0.01 0.14 0.24
Elevated C-reactive protein 18 89.58 % 0.48 0.34 0.63 0.55
Maternal comorbidities
Gestational diabetes 20 39.69 % 0.04 0.02 0.07 0.21
Preeclampsia 20 25.56 % 0.04 0.02 0.07 0.08
Other* 20 63.71 % 0.13 0.08 0.2 0.44
Treatments for COVID-19 infection
Antibiotics 17 96.79 % 0.67 0.41 0.89 0.63
Antivirals 17 96.44 % 0.48 0.24 0.73 0.69
Oxygen support 18 90.99 % 0.31 0.19 0.46 0.71
*

Other included polycystic ovary syndrome, hypothyroidism, hyperthyroidism etc.; P: proportion; CI: confidence interval; I2: measures of heterogeneity across studies; COVID: coronavirus disease.