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. 2020 Jul 22;252:490–501. doi: 10.1016/j.ejogrb.2020.07.034

Table 5.

Comparative evaluation of current systematic review and meta-analysis with other systematic reviews.

Authors Study design Type of study(case series/case reports) Number of studies Sample size (mothers/neonates) C-section Preterm birth LBW Other events Infection transmission Included studies
Trocado [13] et al [77] Systematic Review Mixed (6/2) 8 95/51 94 % 35 % 20 % 1.9 % 1.9 % From China only
Thomas et al [14] Systematic Scoping Review Mixed (7/11) 18 157/160 73 % 20 % 11 % 1 % 6 % Limited countries
Juan et al [15] Systematic Review Mixed (9/15) 24 324/221 78.1 % in case series NR 7.8 % in case reports 1.4 % in case series; 0.5 % in case reports 0.40 % Multiple countries with predominantly case reports. Qualitative separate analysis
Matar et al [16] Systematic Review Mixed(14/10) 24 136/94 76.30 % 37.70 % NR NR 11.50 % Limited countries with weighted analysis without separate analysis for case reports and case series
Huntley et al [17] Systematic Review Case series (13) 13 538/435 84.70 % 20.10 % NR 0.30 % 0 % Limited countries without weighted analysis
Walker et al [18] Systematic Review Mixed (9/40) 49 655/666 55.60 % NR NR 1.20 % 4 % Multiple countries with predominantly case reports
Trippella et al [19] Systematic Review Mixed (18/19) 37 275/248 75 % 23 % NR 0.80 % 8.40 % Multiple countries
Smith et al [20] Systematic Review Mixed (4/5) 9 92/60 80 % 63.80 % 42.80 % 0.20 % 0 % From China only
Kasraeian et al [21] Systematic review and meta-analysis Mixed (NR) 9 87/86 NR 61.20 % NR 0.40 % 0.00 % From China only with weighted analysis without separate analysis for case reports and case series
Yang et al [22] Systematic Review Mixed(10/8) 18 114/84 91 % 21.30 % 5.30 % 2.40 % 0 % From China only
Zaigham and Andersson [11] Systematic Review Mixed (4/14) 18 108 91 % NR NR 1.90 % 0.10 % Limited countries
Muhidin et al [23] Systematic Review Mixed (6/3) 9 89 94 % 33.70 % 7.90 % NR 0 % From China only
Current study Meta-analysis Case series (27) 27 745/505 72 % (91 % in China, 40 % in US, 38 % in Europe) 23 % (17 % in China, 12 % in US, 17 % in US) 7% (5% in China) 2.00 % 1.00 % Multiple countries, separate analysis by location, compared with controls, and association analysis with heterogeneity assessment
Systematic Review Case reports (45) 34 45/43 68.9 % (70 % in China, 50 % in US,78 % in Europe, and 75 % in others) 56 % (45 % in China, 83 % in US,50 % in Europe, and 71 % in others) 35 % (26 % in China, 67 % in US,44 % in Europe, and 17 % in others) 5 % 14 % Multiple countries, separate analysis by location, and association analysis

LBW: low birth weight; NR: not reported; Other events include deaths/still birth or early terminations.