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. 2020 Jul 22;83(6):1730–1737. doi: 10.1016/j.jaad.2020.07.057

Table I.

Activity of antimicrobial ingredients against enveloped viruses such as coronaviruses

Ingredient Virucidal activity against enveloped viruses11,43 Allergenicity
Chloroxylenol High +
Ethanol High -
Povidone iodine High +/-
Sodium hypochlorite (bleach) (0.21%) High -
Triclosan/triclocarban High +/-
Benzalkonium chloride Moderate +
Chlorhexidine digluconate Moderate +
Benzethonium chloride Low -
Phenolic compounds Low -
Quaternary ammonium compounds Low -

High virucidal activity: <1 minute; moderate virucidal activity: 1 to 30 minutes; low virucidal activity: >30 minutes.

The + symbol indicates that the ingredient is found in the American Contact Dermatitis Society core patch testing panels, +/- indicates scattered reports of contact allergy and the - symbol indicates that allergenicity is rare.15,16