Figure 4.

Facial dysmorphology induced by prenatal ethanol exposure. Representative examples of a control animal (A) and a fetus severely affected by ethanol exposure (B). FAS-like phenotype (B) is defined by microcephaly, short palpebral fissures, thin upper vermillion, and smooth philtrum. FAS-like facial features are induced in the mouse by maternal alcohol exposure on gestational day 7 and 8.5 (equivalent to the third gestational week in humans). Courtesy of Prof. Kathie Sulik, University of North Carolina-Chapel Hill (271) (https://www.teratology.org/primer/fas.asp).