Table 2.

Genetic pathways enriched with 156 genes contributing to both preeclampsia and ASD.

Name	GO ID	# of Entities	Overlap	p-value
GO: response to toxic substance	0009636	634	52	4.86E–38
GO: response to extracellular stimulus	0009991	761	53	1.61E–35
GO: response to nutrient levels	0031667	730	52	2.16E–35
GO: positive regulation of locomotion	0040017	666	49	8.86E–34
GO: positive regulation of cell motility	2000147	630	48	8.87E–34
GO: aging	0016280	493	44	1.43E–33
GO: positive regulation of cell migration	0030335	603	47	1.47E–33
GO: positive regulation of cellular component movement	0051272	650	48	2.4E–33
GO: regulation of response to external stimulus	0032101	977	55	6.88E–33
GO: regulation of secretion	0051046	985	54	1.25E–31

For each pathway/GO term, the p-value was calculated using the Fisher exact test against the hypothesis that a randomly selected gene group of the same size (N = 156) can generate a similar or higher overlap with the corresponding pathway/GO term. All these pathways/GO terms passed the FDR correction (q = 0.05).