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. 2020 Jul 15;11:773. doi: 10.3389/fphys.2020.00773

TABLE 7.

Comparison of male characteristics according to total CMS score (Leon-Velarde et al., 2005).

No CMS (≤5) n (%) or median [IQR] Mild total CMS score (6–10) n (%) or median [IQR] Moderate total CMS score (11–14) n (%) or median [IQR] Severe total CMS score (>14) n (%) or median [IQR]
n (%) 1,146 (84) 149 (11.0) 55 (4.0) 9 (1.0)
Age (years) 32 [24; 39] 34 [26; 45]* 33 [23; 43] 40 [33; 40]
Ethnic group
Aymara 53 (4.6) 7 (4.7) 1 (1.8) 1 (11.1)
Quechua 1,093 (95.4) 142 (95.3) 54 (98.2) 8 (88.9)
Residency in La Rinconada (years) 3 [2; 5] 3 [2; 4]* 3 [2; 4] 2 [2; 3]
Hematocrit (%) 60 [55; 65] 67 [65; 73]* 70 [68; 75]* ,+ 63 [63; 75]* ,+
Arterial oxygen saturation (%) 82 [79; 85] 80 [78; 82]* 83 [78; 85]+ 83 [83; 83]+
Heart rate (bpm) 85 [74; 94] 88 [80; 96]* 88 [72; 92] 92 [78; 92]
Diastolic blood pressure (mm Hg) 70 [70; 80] 70 [70; 80] 70 [70; 80] 70 [70; 80]
Systolic blood pressure (mm Hg) 100 [100; 110] 100 [100; 110] 100 [90; 110] 100 [100; 110]
Breathlessness/palpitations
0 943 (82.3) 103 (69.1)* 0 (0)* 0 (0)*
1 115 (10) 32 (21.5)* 24 (43.6)* 9 (100)*
2–3 88 (7.7) 14 (9.4)* 31 (56.4)* 0 (0)*
Sleep disturbance
0 961 (83.9) 118 (79.2) 48 (87.3) 0 (0)* ,+,[dollar]
1–3 185 (16.1) 31 (20.8) 7 (12.7) 9 (100)* ,+,[dollar]
Cyanosis
0 1,074 (93.7) 123 (82.6)* 41 (74.5)* ,+ 9 (100)* ,+
1–3 72 (6.3) 26 (17.4)* 14 (25.5)* ,+ 0 (0)* ,+
Dilatation of veins
0 1,102 (96.2) 143 (96) 30 (54.5)* ,+ 9 (100)* ,+
1–3 44 (3.8) 6 (4) 25 (45.5)* ,+ 0 (0)* ,+
Paresthesia
0 941 (82.1) 85 (57)* 9 (16.4)* ,+ 0 (0)* ,+,[dollar]
1 159 (13.9) 55 (36.9)* 40 (72.7)* ,+ 0 (0)* ,+,[dollar]
2–3 46 (4) 9 (6)* 6 (10.9)* ,+ 9 (100)* ,+,[dollar]
Headache
0 928 (81) 102 (68.5)* 23 (41.8)* ,+ 0 (0)* ,+
1–3 218 (19) 47 (31.5)* 32 (58.2)* ,+ 9 (100)* ,+
Tinnitus
0 1,010 (88.1) 128 (85.9) 19 (34.5)* ,+ 0 (0)* ,+,[dollar]
1–3 136 (11.9) 21 (14.1) 36 (65.5)* ,+ 9 (100)* ,+,[dollar]
Hematocrit
0 720 (62.8) 0 (0)* 0 (0)* 0 (0)*
3 426 (37.2) 149 (100)* 55 (100)* 9 (100)*

IQR, interquartile range; CMS, chronic mountain sickness. Scores of symptom severity were grouped when the number of subjects per score was too small to allow statistical analysis. * Significantly different from subjects with no CMS. +Significantly different from subjects with mild total CMS score. $Significantly different from subjects with moderate total CMS score (p < 0.05).