TABLE 3.
CETP, PLTP, and LCAT activity in healthy adults with overweight and obesity at baseline and after 5 wk of consumption of LF, MF, or AV diet1
| Lipid transfer protein activity | Baseline (n = 45) | LF (n = 43) | MF (n = 42) | AV (n = 43) | Treatment effect (P ) |
|---|---|---|---|---|---|
| CETP, pmol/(μL·h) | 55.3 ± 1.4 | 52.8 ± 1.5a,b,* | 54.4 ± 1.2a | 52.1 ± 1.2b,* | 0.02 |
| PLTP, pmol/(μL·h) | 20.3 ± 0.6 | 19.7 ± 0.7 | 20.0 ± 0.8 | 20.6 ± 0.7 | 0.5 |
| LCAT, % change | 6.2 ± 0.5 | 8.5 ± 0.7 | 8.0 ± 0.6 | 9.0 ± 0.7 | 0.5 |
1All values are means ± SEMs (n = 42–45). Values with different superscript letters differ (P < 0.05). *Significant change compared with baseline average American diet, P< 0.05. AV, avocado diet; CETP, cholesteryl ester transfer protein; LCAT, lecithin/cholesterol acyltransferase; LF, lower-fat diet; MF, moderate-fat diet; PLTP, phospholipid transfer protein.