Table 1.
Factor | Total, n (%) | RON |
MET |
RON and MET co-expression |
||||||
---|---|---|---|---|---|---|---|---|---|---|
Low | High | p-value | Low | High | p-value | Low | High | p-value | ||
Age | ||||||||||
Mean±SD | 52.82±12.44 | 51.77 | 54.89 | 0.165 | 52.27 | 53.92 | 0.413 | 52.03 | 55.47 | 0.113 |
Lymph node metastasis | ||||||||||
Yes | 48 (25.7) | 28 | 20 | 0.175 | 33 | 15 | 0.678 | 37 | 11 | 0.999 |
None | 139 (74.3) | 96 | 43 | 91 | 48 | 107 | 32 | |||
Distant metastasis | ||||||||||
Yes | 19 (10.2) | 11 | 8 | 0.413 | 11 | 8 | 0.413 | 13 | 6 | 0.348 |
None | 168 (89.8) | 113 | 55 | 113 | 55 | 131 | 37 | |||
TNM stage | ||||||||||
Stage I | 85 (45.5) | 58 | 27 | 0.212 | 58 | 27 | 0.750 | 65 | 20 | 0.982 |
Stage II | 85 (45.5) | 58 | 27 | 56 | 29 | 66 | 19 | |||
Stage III | 17 (9.1) | 8 | 9 | 10 | 7 | 13 | 4 | |||
Differentiation | ||||||||||
Well | 1 (0.5) | 0 | 1 | 0.488 | 0 | 1 | 0.341 | 0 | 1 | 0.326 |
Moderate | 20 (10.7) | 12 | 8 | 11 | 9 | 15 | 5 | |||
Poor | 147 (78.6) | 99 | 48 | 100 | 47 | 114 | 33 | |||
Unknown | 19 (10.2) | 13 | 6 | 13 | 6 | 15 | 4 | |||
Treatment | ||||||||||
Chemotherapy | 161 (86.1) | 108 | 53 | 0.539 | 106 | 55 | 0.735 | 126 | 35 | 0.310 |
None | 26 (13.9) | 16 | 10 | 18 | 8 | 18 | 8 | |||
Surgical procedures | ||||||||||
Conserving surgery | 29 (15.5) | 21 | 8 | 0.656 | 22 | 7 | 0.496 | 24 | 5 | 0.427 |
Simple mastectomy | 76 (40.6) | 48 | 28 | 49 | 27 | 55 | 21 | |||
Radical mastectomy | 82 (43.9) | 55 | 27 | 53 | 29 | 65 | 17 | |||
Tumor size (cm3) | ||||||||||
≥ 5 | 88 (47.1) | 57 | 31 | 0.675 | 54 | 34 | 0.177 | 66 | 22 | 0.539 |
< 5 | 99 (52.9) | 67 | 32 | 70 | 29 | 78 | 21 |