Table 2.
Echocardiographic data of two subgroups at baseline and 12 months after treatment
| Echocardiographic data | Device group | Control group | F, P value * | ||||
|---|---|---|---|---|---|---|---|
| Baseline | Follow‐up | P value | Baseline | Follow‐up | P value | ||
| MR EF (%) | 3.7 ± 0.4 | 1.7 ± 0.8 | <0.001 | 3.4 ± 0.5 | 3.35 ± 0.98 | 0.694 | 58, <0.001 |
| 31.9 ± 8.4 | 33.2 ± 9.8 | 0.178 | 32.8 ± 6.4 | 33 ± 6.5 | 0.893 | 0.43, 0.51 | |
| LVEDV (mL) | 219 ± 74 | 193 ± 66 | 0.001 | 214 ± 62 | 224 ± 52 | 0.442 | 6.69, 0.01 |
| LVESV (mL) | 152 ± 68 | 136 ± 43 | 0.004 | 144 ± 48 | 148 ± 44 | 0.611 | 12.4, 0.001 |
| LA volume (mL) | 140 ± 69 | 119 ± 59 | <0.001 | 125 ± 64 | 132 ± 56 | 0.343 | 12.9, 0.001 |
| GLS (%) | ‐8.6 ± 3.7 | ‐8.6 ± 3.7 | 0.922 | −9.8 ± 3.5 | −9.9 ± 3.9 | 0.893 | 0.002, 0.96 |
| PALS (%) | 7.6 ± 4.6 | 7.3 ± 4.6 | 0.678 | 7.4 ± 4.2 | 7.9 ± 4.2 | 0.646 | 0.18, 0.67 |
| GWI (mmHg%) | 607 ± 282 | 650 ± 260 | 0.045 | 686 ± 338 | 618 ± 315 | 0.287 | 3.8, 0.04 |
| GCW (mmHg%) | 854 ± 288 | 949 ± 325 | <0.001 | 850 ± 305 | 833 ± 366 | 0.795 | 3.42, 0.04 |
| GWW (mmHg%) | 138 ± 65 | 131 ± 75 | 0.623 | 152 ± 105 | 191 ± 120 | 0.025 | 4.0, 0.04 |
| GWE (%) | 80 ± 10 | 82 ± 8 | 0.147 | 81 ± 11 | 76 ± 14 | 0.032 | 6.0, 0.02 |
EF, ejection fraction; EROA, effective regurgitant orifice area; GCW, global constructed work; GLS, global longitudinal strain; GWE, global work efficiency; GWI, global work index; GWW, global wasted work; LA, left atrial; LVEDV, left ventricular end diastolic volume; LVESV, left ventricular end systolic volume; MR, mitral regurgitation; PALS, peak atrial longitudinal strain.
*
F, P values refer to the interaction term of mitral clip vs. optimal medical treatment for differences of echocardiographic data between the baseline and follow‐up, P values by post hoc analysis with Bonferroni correction.