Table 4.
Baseline echocardiography and clinical characteristics of MitraClip patients according to reverse remodelling (reduction of 10% of LVESV)
| Baseline clinical and echocardiography data | ΔLVESV >10% | ΔLVESV <10% | P value |
|---|---|---|---|
| Log EuroSCORE (%) | 21.3 ± 13.4 | 27 ± 17.6 | 0.273 |
| BNP (pg/mL) | 1115 ± 1324 | 853 ± 738 | 0.471 |
| NYHA Class | 3.1 ± 0.7 | 3.2 ± 0.5 | 0.339 |
| 6MWD (m) | 232 ± 143 | 257 ± 147 | 0.599 |
| Dilated cardiomyopathy (%) | 35 ± 49 | 31 ± 47 | 0.783 |
| GLS (%) | −9.2 ± 4.6 | −8.0 ± 2.9 | 0.369 |
| LVEDV (mL) | 232 ± 72 | 209 ± 77 | 0.1 |
| LVESV (mL) | 164 ± 68 | 140 ± 66 | 0.12 |
| EF (%) | 32 ± 10 | 31 ± 8 | 0.750 |
| EROA (mm2) | 35 ± 21 | 27 ± 12 | 0.132 |
| GWI (mmHg%) | 706 ± 392 | 568 ± 187 | 0.07 |
| GCW (mmHg%) | 1011 ± 343 | 762 ± 206 | 0.002 |
| GWW (mmHg%) | 131 ± 71 | 123 ± 62 | 0.797 |
| GWE (%) | 79 ± 10 | 81 ± 10 | 0.656 |
ΔLVESV is the reduction of 10% of LVESV (upper tercile of the study cohort).
EF, ejection fraction; EROA, effective regurgitant orifice area; GCW, global constructed work; GLS, global longitudinal strain; GWE, global work efficiency; GWI, global work index; GWW, global wasted work; LA, left atrial; LVEDV, left ventricular end diastolic volume; LVESV, left ventricular end systolic volume; MR, mitral regurgitation; PALS, peak atrial longitudinal strain.