Table 1.
Main chemical components in various humidifier disinfectants in 447 children with HD-ILDs (listed by brand name)
| Brand names of the humidifier disinfectant | Main chemical component | Number of HD-ILDs (%) [18] |
|---|---|---|
| Oxy Saksak | PHMG phosphate | 176 (39.4) |
| Cefu | PGH | 27 (6.0) |
| Aekyung Home Clinic | CMIT/MIT | 22 (4.9) |
| E-mart Eplus | CMIT/MIT | 2 (0.4) |
| Lotte Mart Wiselect | PHMG phosphate | 13 (2.9) |
| Homeplus | PHMG phosphate | 3 (0.7) |
| Vegetable clean-up | PHMG phosphate | 0 (0.0) |
| Mixed brands | 204 (45.6) | |
| Brands with PHMG-P | PHMG-P | 42 (9.4) |
| Brands with a mixture of CMIT/MIT | CMIT/MIT | 2 (0.4) |
| Brands with a mixture of ingredients | 160 (35.8) | |
| Total | 447 (100) |
Patients with HD-ILDs included those in whom more than a possible degree of associationa) was found between HD usage and development of HD-ILDs.
HD-ILDs, humidifier disinfectant-associated interstitial lung diseases; PHMG, polyhexamethylene guanidine; PGH, [oligo(2-(2-ethoxy)ethoxyethyl guanidinium chloride]; CMIT, chloromethylisothiazolinone; MIT, methylisothiazolinone.
a)
A possible degree of association means cases with incomplete clinical features and radiological and pathological findings of HD-ILDs and therefore needs additional considerations on other subtypes of ILDs.