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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Eur J Cancer. 2020 Jun 27;135:211–220. doi: 10.1016/j.ejca.2020.05.005

Table 3.

Chronic effects that developed from anti–PD-1 therapy.

Melanoma
(n = 135)
RCC
(n = 44)
NSCLC
(n = 38)
Total
(n = 217)
Adrenal insufficiency 6 (4.44%) 0 1 (2.63%) 7 (3.23%)
Arthritis/arthralgias 6 (4.44%) 1 (2.27%) 0 7 (3.23%)
Dermatitis 2 (1.48%) 0 0 2 (0.92%)
Diabetes 0 2 (4.54%) 0 2 (0.80%)
Dysphagia 1 (0.74%) 0 0 1 (0.46%)
Hypothyroidism 12 (9.45%) 6 (13.64%) 4 (10.52%) 22 (10.14%)
Neuropathy 4 (2.96%) 1 (2.27%) 1 (2.63%) 6 (2.76%)
Pneumonitis 3 (2.22%) 1 (2.27%) 0 4 (1.84%)

anti–PD-1, antibodies to programmed death-1 receptor.