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The IC50s for the top three compounds are less than 10 μM. The IC50s for NP001-1C11, NP002-1D9, and NP003-2B11 are 5.143 μM, 5.025 μM, and 9.659 μM, respectively. IC50 values were calculated from proteolytic activity assays similar to those shown in Fig. 5.
