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. 2020 May 18;123(2):298–306. doi: 10.1038/s41416-020-0872-0

Fig. 2. KSHV infection promotes the release of pro-tumorigenic cytokines.

Fig. 2

a IL-10, VEGF, IL-8, IL-6 and IFN-γ released by KSHV- and mock-infected macrophages were measured by Luminex assay. Mean plus SD of three different experiments is reported. *p-value < 0.05; b Morphology of KSHV-infected HUVEC plus supernatant of KSHV-infected macrophages (sup KSHV-MΦ), KSHV-infected HUVEC, Mock HUVEC, Mock HUVEC treated with supernatant of KSHV-infected macrophages (sup KSHV-MΦ) or treated with supernatant of UV-KSHV-exposed macrophages (sup UV-KSHV-MΦ) was observed utilising an optical microscope (×40 magnification); c Snail expression in mock-, KSHV-infected and KSHV-infected HUVEC plus sup KSHV-MΦ was evaluated by western blot analysis. β-actin (β-ACT) was used as loading control. A representative experiment out of three is shown. Histograms represent the mean plus S.D. of the densitometric analysis of the ratio of snail/β-actin. *p-value < 0.05.