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. 2020 Jul 21;11(7):553. doi: 10.1038/s41419-020-02747-9

Fig. 5. CircTADA2A inactivated lung fibroblasts via Cav1.

Fig. 5

LL-24 cells were transfected with a si-circTADA2A or Ad-Cav1+si-circTADA2A or Ad-GFP + si-circTADA2A or b Ad-circTADA2A or Ad-GFP or Ad-circTADA2A+si-control or Ad-circTADA2A+si-Cav1, and then stimulation with 5% FCS or 60 ng/ml PDGF-BB or 200 ng/ml IGF-1 or 10 ng/ml TGF-β1 for 6 h. The expression of COL1A1, COL3A1, LN, FN, and α-SMA were measured by western blot, and the cell proliferation was measured by BrdU incorporation assay. **P < 0.01.