Table 2.
Association of AKI with development of incident CKD and progression of CKD
| Nested model | HR (95% CI) of AKI vs. no AKI on kidney outcomes |
|
|---|---|---|
| Incident CKD | CKD progression | |
| Model 1: matcheda cohort | 3.41 (2.35–4.95) | 2.30 (1.32–3.99) |
| Model 2: model 1 + sex; race/ethnicity; sepsis during index admission; 3-mo baseline visit smoking status, diabetes status, and body mass index | 3.98 (2.51–6.31) | 2.37 (1.28–4.39) |
AKI, acute kidney injury; CI, confidence interval; CKD, chronic kidney disease; HR, hazard ratio.
a
Matching variables included clinical center, age, preindex admission estimated glomerular filtration rate, preindex admission diabetes status, prior cardiovascular disease, and intensive care unit stay during index admission.