Table 2.
Baseline characteristics of the subjects according to 28-day mortality.
| Characteristics | Survivors (n = 270) | Nonsurvivors (n = 35) | P |
|---|---|---|---|
| Males (%) | 68.9 | 65.7 | 0.7 |
| Ages (years) | 54.3 ± 15.5 | 63.3 ± 15.0 | 0.001 |
| Principal diagnosis leading to ICU admission (%) | <0.001 | ||
| Sepsis or sepsis shock | 8.6 | 25.7 | |
| Severe trauma | 50 | 5.7 | |
| Brain injury or diseases | 22.2 | 31.5 | |
| Severe disease | 6.3 | 17.1 | |
| After operation | 10.7 | 8.6 | |
| Tumor | 1.9 | 11.4 | |
| Pulmonary embolism | 0.7 | 0 | |
| APACHE II score | 11.19 ± 6.49 | 24.23 ± 9.60 | <0.001 |
| GCS score | 12.81 ± 4.09 | 7.43 ± 5.21 | <0.001 |
| SOFA score | 4.46 ± 3.14 | 10.00 ± 5.21 | <0.001 |
| FT3 (pmol/L) | 2.77 ± 0.37 | 2.53 ± 0.47 | 0.009 |
| FT4 (pmol/L) | 11.95 ± 2.71 | 11.14 ± 3.25 | 0.22 |
| TSH (mIU/L) | 1.81 ± 5.70 | 1.06 ± 1.21 | 0.537 |
| Vital signs when enrolled | |||
| T (°C) | 37.27 ± 0.84 | 37.36 ± 1.10 | 0.565 |
| HR | 93.1 ± 29.7 | 103.8 ± 34.7 | 0.052 |
| SBP (mmHg) | 127.56 ± 31.72 | 99.06 ± 35.41 | <0.001 |
| DBP (mmHg) | 69.61 ± 18.37 | 56.38 ± 22.84 | 0.002 |
| R | 22.1 ± 9.9 | 23.4 ± 19.8 | 0.524 |
| ALB (g/L) | 29.04 ± 7.11 | 26.57 ± 6.66 | 0.049 |
| PCT (μg/L) | 3.21 ± 8.51 | 9.77 ± 17.03 | 0.002 |
| BNP(pg/mL) | 439.1 ± 937.3 | 1193.0 ± 1301.4.4 | 0.005 |
| WBC (×109/L) | 11.3 ± 5.1 | 17.0 ± 11.1 | <0.001 |
| HGB (g/L) | 104.7 ± 21.7 | 99.9 ± 30.7 | 0.242 |
| PLT (×109/L) | 151.4 ± 102.5 | 113.0 ± 84.7 | 0.035 |
| PT (s) | 13.7 ± 8.35 | 15.2 ± 6.94 | 0.329 |
| APTT (s) | 31.1 ± 13.2 | 32.9 ± 20.3 | 0.488 |
| FIB (g/L) | 3.35 ± 1.52 | 3.21 ± 4.15 | 0.697 |
| Lac (mmol/L) | 2.48 ± 6.91 | 5.08 ± 6.53 | 0.041 |
| pH | 7.32 ± 0.94 | 7.32 ± 0.17 | 0.937 |
| BE (mmol/L) | −1.45 ± 4.62 | −6.46 ± 8.45 | <0.001 |
| PCO2 (mmHg) | 35.05 ± 10.50 | 36.56 ± 18.14 | 0.676 |
| Oxygenation index (PaO2/FIO2) | 287.3 ± 141.2 | 205.5 ± 104.8 | 0.001 |
| CREA (μmol/L) | 81.9 ± 99.8 | 204.5 + 214.4 | <0.001 |
| TBil (mmol/L) | 27.9 ± 35.2 | 40.3 ± 60.4 | 0.085 |
| Na (mmol/L) | 137.7 ± 16.1 | 139.7 ± 27.4 | 0.532 |
| K (mmol/L) | 3.81 ± 0.77 | 3.80 ± 1.28 | 0.931 |
APACHE II score: acute physiology and chronic health evaluation II score; GCS: Glasgow coma scale; SOFA; sequential organ failure score; fT3: free triiodothyronine; FT4: free thyroxine; TSH: thyroid-stimulating hormone; SBP: systolic blood pressure; DBP: diastolic blood pressure; PCT: procalcitonin; BNP: brain natriuretic peptide; HGB: hemoglobin; PLT: blood platelet; CREA: creatinine; TBil: total bilirubin; PT: prothrombin time; APTT: activated partial thromboplastin time; FIB; fibrinogen.