Table 4.
Univariable and multivariable logistic regression analyses for 28d mortality.
| Univariable | Multivariable | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | |
| NTIS | 3.531 | (1.68, 7.41) | 0.001 | 2.966 | (1.272, 6.915) | 0.012 |
| FT3 | 0.433 | (0.26, 0.722) | 0.001 | |||
| FT4 | 1.01 | (0.941, 1.083) | 0.789 | |||
| FT4/FT3 | 1.426 | (1.121, 1.814) | 0.004 | |||
| TSH | 0.837 | (0.585,1.197) | 0.329 | |||
| APACHE II | 1.231 | (1.160, 1.308) | <0.001 | |||
| SOFA | 1.378 | (1.248, 1.520) | <0.001 | |||
| The duration of MV (h) | 1.002 | (1.000, 1.003) | 0.046 | |||
| Lactic acid (mmol/L) | 1.03 | (0.991, 1.072) | 0.137 | |||
| CREA (μmol/L) | 1.005 | (1.002, 1.007) | <0.001 | |||
| Oxygenation index | 0.995 | (0.992, 0.998) | 0.003 | 0.995 | (0.991, 0.999) | 0.007 |
| WBC | 1.121 | (1.062, 1.183) | <0.001 | 1.118 | (1.052, 1.187) | <0.001 |
| ALB | 0.962 | (0.925, 1.000) | 0.049 | 1.004 | (1.002, 1.007) | 0.001 |
| Age (years) | 1.045 | (1.016, 1.075) | 0.002 | |||
| BNP | 1.001 | (1.000, 1.001) | 0.003 | |||
Variables included in the multivariable logistic analysis were NTIS, the duration of MV, CREA, oxygenation index, WBC, ALB, and age. NTIS: nonthyroidal illness syndrome; FT3: free triiodothyronine; FT4: free thyroxine; TSH: thyroid-stimulating hormone; APACHE II score: acute physiology and chronic health evaluation II score; SOFA: sequential organ failure score; MV: mechanical ventilation; CREA: creatinine; WBC: white blood cell; ALB: albumin; BNP: brain natriuretic peptide.