Table 1.

PI data.

Patient	Age, sex	Primary diagnosis	Time to PI after Tx	Time to PI after GJ tube	Immunosuppression	Symptoms	PI distribution	Pneumoperitoneum	Mesenteric gas	Portal venous gas	Lactic acid	Amylase	Bicarbonate	Follow-up imaging	Management
1	58, M	Sarcoidosis	23	11	P+T+MMF	Abdominal pain, diarrhea	C/A	Y	Y	N	23.5	45	28	XR × 4	NPO × 2 days O2 at 15 L Vancomycin, Zosyn, Micafungin
2	43, M	IPF	47	43	P+T+MMF	None	C/A/T/D	N	N	N	1.9		23	XR × 3 CT × 1	NPO × 4 days O2 at 15 L Flagyl, Merrem
3	71, F	IPF	53	3	P+T+MMF	N/V/D × 2 days	C/A/T	N	N	N	1.4		29	XR × 9	NPO × 3 days O2 at 15 L Flagyl
4	66, F	Sarcoidosis	36	4	P+T+MMF+IVIG	N/V × 3 days	A/T	Y	N	N	1.6	31	23	None	OR for ex lap O2 at 15 L (negative) NPO × 1 day
5	67, F	IPF	517	519	P+T+MMF	Diarrhea	A	Y	N	N	0.7	17	25	XR × 3	Flagyl × 14 d O2 at 15 L CLD × 1 day
6	66, F	IPF	147		P+T+MMF	Pain × 4 weeks N/V × 4 months	C/A	N	N	N	1.1		23	XR × 6	O2 at 15 L NPO × 2 days
7	64, M	IPF	8	10	P+T+MMF	Diarrhea	C/A	N	Y	Y			29	XR × 1	NPO × 1 day O2 at 15 L
8	59, M	Scleroderma ILD	5		P+T+MMF	None	C	Y	Y	N			37	XR × 2	OR surgery—cecal ischemia and perforation and closed loop large bowel obstruction
9	69, F	Scleroderma ILD	41	45	P+T+MMF	Bloating × 3 weeks	C/A/T	Y	Y	N	2.2	90	23	XR × 1	Flagyl O2 at 15 L NPO × 1 day
10	37, F	Scleroderma ILD	28	38	P+T+MMF	None	C/A/T/D	Y	Y	N	0.9		24	XR × 3	O2 at 15 L NPO × 1 d
11	79, M	IPF	375		P+T+MMF	None	C/A	Y	N	N	2	39	23	CT × 2 XR × 1	O2 at 15 L NPO × 1 d
12	54, F	IPF	28	37	P+T+MMF	None	C/A/T/D	Y	Y	N	1.6		26	XR × 1	Flagyl O2 at 15 L Switched TF to Vivonex
13	71, M	IPF	209	10	P+T+MMF	N/V/D × 10 d	C	N	N	Y	1.6		28	XR × 5	NPO × 1 d Flagyl O2 at 15 L
14	61, F	Scleroderma ILD	47	53	P+T+MMF	None	C/A/T	Y	Y	N	2.6		24	XR × 3	NPO × 1 d O2 at 15 L Zosyn
15	73, M	CPFE	37	45	P+T+MMF	Diarrhea	C/A/T	Y	Y	N	3.3	74	28	CT × 2 XR × 4	NPO × 3 days O2 at 15 L Flagyl/Vancomycin (C. diff)
16	61, M	IPF	63	21	P+T+MMF	Diarrhea	C/A/T/D	Y	Y	N	1.8	38	25	XR × 4	Switch TF to elemental Flagyl, Florastor O2 at 15 L
17	59, F	IPF	234	193	P+T+MMF	None	C/A/T/D	N	N	N	0.5		24	None	Patient seen in ED after outside X-ray showing PI, discharged from ED
18	43, M	IPF	200	108	P+T+MMF	None	A/T	Y	Y	N	1.8	34	25	XR × 7	Switch TF to elemental O2 at 15 L Flagyl
19	71, M	IPF	24	13	P+T+MMF	None	C	Y	N	N	1.5		26	None	Treated outpatient
20	58, M	A1AT	17	28	P+T+MMF	Diarrhea	C/A/T/D	Y	Y	N	0.6	120	30	XR × 2	NPO × 1 day Flagyl O2 at 15 L
21	55, M	IPF	1477	30	P+T	None	C/A	N	Y	N	1.5	23	36	XR × 3	NPO × 1 day O2 at 15 L
22	69, M	IPF	51	39	P+T+MMF	None	C/A/T	Y	Y	N	0.8	40	29	None	NPO × 1 day O2 at 15 L
23	62, M	IPF	202		P+T+MMF	Emesis × 1	C/A/T	N	N	N	1		22	XR × 3	NPO × 1 day O2 at 15 L

Note: IPF: interstitial pulmonary fibrosis; P: prednisone; T: tacrolimus; MMF: mycophenolate mofetil; C/A/T/D: cecum/ascending/transverse/descending colon.