Table 2.
Cell cycle phase distribution (%) of the tumor cell lines after their treatment with different solvent extracts of Saussurea costus. Results were expressed as mean ± SD for three independent replicates.
| Tumor cell | Extracts | Cell phases | ||
|---|---|---|---|---|
| G1 | S | G2/M | ||
| MCF-7 | Cell control | 50.32 ± 0.98 | 23.21 ± 0.6 | 26.47 ± 0.9 |
| Methanol | 63.42 ± 1.5 | 5.87 ± 0.5 | 30.71 ± 1.01 | |
| Hexane | 68.92 ± 0.9 | 13.45 ± 1.1 | 17.63 ± 0.52 | |
| Chloroform | 64.25 ± 0.5 | 11.43 ± 0.7 | 24.32 ± 0.6 | |
| Ethyl acetate | 67.82 ± 0.7 | 12.65 ± 1.1 | 19.53 ± 0.8 | |
| Butanol | 54.71 ± 1.1 | 12.08 ± 0.5 | 33.21 ± 0.7 | |
|
| ||||
| HepG2 | Cell control | 56.44 ± 1.1 | 24.58 ± 1.1 | 18.98 ± 2.1 |
| Methanol | 66.87 ± 1.5 | 13.76 ± 1.16 | 19.37 ± 1.1 | |
| Hexane | 69.11 ± 2.2 | 12.12 ± 1 | 18.77 ± 1.3 | |
| Chloroform | 58.25 ± 0.4 | 18.31 ± 1.4 | 23.44 ± 1 | |
| Ethyl acetate | 56.74 ± 0.8 | 20.9 ± 1 | 22.36 ± 1.6 | |
| Butanol | 61.39 ± 1.7 | 16.3 ± 1.7 | 22.31 ± 0.9 | |
|
| ||||
| HCT116 | Cell control | 48.54 ± 2.3 | 23.13 ± 1.4 | 28.33 ± 1.1 |
| Methanol | 59.35 ± 1.3 | 6.91 ± 1 | 33.74 ± 1.7 | |
| Hexane | 68.2 ± 2.7 | 16.13 ± 1.3 | 15.66 ± 1.6 | |
| Chloroform | 56.8 ± 1.3 | 11.1 ± 1.4 | 32.1 ± 0.8 | |
| Ethyl acetate | 66.87 ± 1.8 | 20.48 ± 0.8 | 12.65 ± 1.5 | |
| Butanol | 51.87 ± 2.5 | 16.61 ± 1.7 | 31.52 ± 1.4 | |