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. 2020 Jul 15;14:193. doi: 10.3389/fncel.2020.00193

Figure 1.

Figure 1

FK506 binding protein 5 (FKBP5) was upregulated notably in acute ischemic stroke (AIS) patients. (A) Expression of FKBP5 in plasma of AIS patients (n = 50) and healthy controls (n = 50) examined by real-time qPCR. (B) Expression of FKBP5 in plasma of AIS patients (n = 50) and healthy controls (n = 50) tested by ELISA. Data are presented as the mean ± SD. *P < 0.05 vs. health control group. (C) Linear regression analysis was applied in each individual between the FKBP5 expression and National Institute of Health Stroke Scale (NIHSS) score, **P < 0.01. (D) Receiver-operator characteristic (ROC) curve of FKBP5 in the diagnosis of AIS (n = 50). (E) Linear regression analysis of the relationship between FKBP5 expression and diffusion-weighted imaging (DWI) volume of lesion, **P < 0.01.