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. 2020 Jun;64:50–57. doi: 10.1016/j.ceb.2020.02.002

Figure 2.

Figure 2

Selected summary of regulators of ZGA, loops and TAD border insulation in human (Homo sapiens), mouse (Mus musculus), fruit fly (Drosophila melanogaster) and zebrafish (Danio rerio) development. Essential proteins for each process are highlighted in green, proteins that are known to be present but have not been experimentally tested are highlighted in gray, and proteins with tested minor roles are highlighted in beige. ZGA, zygotic genome activation; TADs, topologically associating domains.