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. 2020 Jan 30;50(8):2710–2722. doi: 10.1007/s10803-020-04382-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — ROIs for ¹H-MRS data acquisition. ROIs were placed in the left M1 and left SMA with a voxel size of 20 × 20 × 20 mm³. The M1 ROI was placed in the left precentral sulcus, and the midpoint of the SMA ROI was set as the upper part of the Brodmann area 6. The ROIs in the M1 and SMA areas included slightly the primary somatosensory cortex (S1) and premotor cortex (PMC), respectively. For both ROIs, the inclusion of bone and cerebrospinal fluid was avoided