Table 3.

Linear regression models of consults called per year by a spoke as a predictor of a spoke’s alteplase treatment outcomes of interest with and without adjustment for spoke-level characteristics.

Spoke variable	Median door-to-needle time (minutes)				Number treated with alteplase per year				Percent of eligible patients treated with alteplase
	Unadjusted		Adjusted		Unadjusted		Adjusted		Unadjusted		Adjusted
	β	p	β	p	β	p	β	p	β	p	β	p
Consults called per year (units of 10)	−1.57	0.02	−1.76	0.02	2.00	<0.01	1.68	<0.01	13.39	<0.01	8.27	<0.01
Number of staffed beds (units of 10)	0.04	0.80	0.21	0.17	0.14	<0.01	0.06	0.05	0.29	0.75	−0.04	0.94
Rurality	−5.84	0.29	−12.12	0.05	−2.57	0.19	0.10	0.95	11.30	0.68	33.92	0.13
Teaching status	5.49	0.31	0.72	0.87	1.01	0.52	0.26	0.77	7.20	0.80	−5.15	0.76
Primary Stroke Center certification	5.74	0.27	−1.20	0.82	1.39	0.42	0.50	0.63	12.38	0.63	−0.61	0.98
Median age	0.10	0.82	0.02	0.97	−0.01	0.96	−0.02	0.84	−0.21	0.92	−0.07	0.97
Percent Caucasian	0.12	0.59	−0.64	0.03	0.04	0.59	0.04	0.54	−1.69	0.13	−1.91	0.07
Percent female	−0.02	0.97	0.52	0.33	0.18	0.34	−0.06	0.60	2.00	0.46	−0.19	0.92
Percent history of atrial fibrillation	1.15	0.12	1.24	0.19	0.00	1.00	−0.13	0.61	5.14	0.16	2.59	0.46
Median NIHSS	3.10	0.02	0.48	0.77	0.02	0.97	0.14	0.64	−3.72	0.48	3.50	0.56

Abbreviations: Beta-coefficient (β); P-value (p); National Institute of Health Stroke Severity (NIHSS)