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. Author manuscript; available in PMC: 2020 Jul 22.
Published in final edited form as: Gene Ther. 2014 Apr 3;21(6):566–574. doi: 10.1038/gt.2014.29

Figure 6. DermaPrep administration of liquid vaccine.

Figure 6.

(a) The skin treatment starts with shaving and disinfection, then the body sponge is used to exfoliate the epidermis; (b) Tape stripping for the removal of the residual skin material (e.g.: dead cells); (c) Transparent film (the “patch”) designed to keep liquid vaccine in contact with the exfoliated epidermis for several hours without leaking. Liquid vaccine administered under the patch is completely dried after three hours, potentially improving the degree of penetration seen in earlier animal experiments where the liquid nanoparticles were dried within 30 minutes without the use of the patch.