Table 3.
Comparison of the Sensing Properties of Different Genosensors for the Detection of DENV.
| Sensing Interface | Method/Target | Dynamic Range | LOD | Ref. |
|---|---|---|---|---|
| pDNA2-liposome/biotin-pDNA1-SMB | Fluorescence/synthetic DNA and RNA amplicon | 0.125 nM–50 pM | 0.125 nM | [39] |
| SH-pDNA-AuNP | QCM/PCR 130mtDNA amplicon | 2 × 100–2 × 106 PFU/mL | 2 PFU/mL | [40] |
| pDNA/IEM | I-V curve/RT-PCR DNA amplicon | -- | 0.17 aM | [41] |
| NH2-pDNA/APS/Pt/AAO | EIS or DPV/synthetic 30mtDNA | 1 pM–1 μM | 2.7 pM | [15] |
| pDNA/PGE | DPV/synthetic 22mtDNA | 10–100 nM | 3.1 nM | [18] |
| NH2-pDNA/chitosan/ZnO/Pt-Pd/FTO | CV/synthetic 35mtDNA | 1–100 μM | 43 μM | [19] |
| NH2-pDNA/MPA/Mn2O3 nanofiber/GCE | EIS or DPV/synthetic consensus dengue primer | 1 aM–1 μM | 0.12 aM | [20] |
| ITO | LSV/pDNA-RNA amplicon mixture | -- | 2 amol | [26] |
| pDNA/SiO2@APTES-GO/Pt | EIS/extracted RNA | -- | 1 fM | [16] |
| NH2-pDNA/MHA/MCH/Au | EIS/extracted RNA | 102–105 PFU/mL | 20 PFU/mL (~20 aM) | This work |
AAO: anodic aluminum oxide, APS: 3-aminopropyltrimethoxysilane, DPV: differential pulse voltammetry, FTO: fluorine doped tin oxide, IEM: ion-exchang nanomembrane sensor, I-V: current-voltage, LSV: linear sweep voltammetry, SMB: streptavidin magnetic bead, MPA: mercaptopropionic acid, PGE: pencil graphite electrode, QCM: quartz crystal microbalance, SPR: surface plasmon resonance, LOD: limit of detection.