Table 2.

Sensitivity, specificity, positive predictive value, and negative predictive values of the optimal cutoff by Youden index for FRAX® MOFP score, FRAX® HFP score, and OSTA index to identify Osteoporosis on DXA.

Threshold	Sensitivity (95% CI)	Specificity (95% CI)	PPV (95% CI)	NPV (95% CI)
FRAX® MOFP score ≥ 3.7%	0.78 (0.73–0.83)	0.63 (0.59,0.66)	0.4 (0.36–0.44)	0.9 (0.87–0.92)
FRAX® HFP score ≥ 0.6%	0.85 (0.80–0.89)	0.58 (0.55–0.62)	0.39 (0.35–0.43)	0.92 (0.9–0.94)
OSTA Index ≤ −1.2	0.76 (0.70–0.81)	0.74 (0.71–0.77)	0.48 (0.43–0.54)	0.91 (0.88–0.93)

MOFP, Major Osteoporotic Fracture Probability; HFP, Hip Fracture Probability; OSTA, Osteoporosis Self-Assessment Tool for Asians; DXA, dual energy X-ray absorptiometry; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value.