Table 6.
Receiver operating characteristic area under the curve (95% confidence intervals) for prediction of outcome in high risk women, using CVF cathelicidin concentration stratified by gestation at sampling, after exclusion of samples taken once prophylactic intervention had been initiated.
| Outcome | Cathelicidin receiver operating characteristic area under the curve (95% confidence interval) | |||
|---|---|---|---|---|
| Gestation category (weeks+days) | ||||
| 10–13+6 | 14–15+6 | 16–19+6 | 20–24 | |
| Cervical shortening < 25 mm | 0.58 (0.51–0.66) | 0.58 (0.50–0.65) | 0.58 (0.51–0.65) | 0.49 (0.41–0.57) |
| sPTB < 37 w | 0.64 (0.56–0.71) | 0.75 (0.68–0.81) | 0.61 (0.53–0.68) | 0.58 (0.50–0.65) |
| sPTB < 34 w | 0.58 (0.51–0.66) | 0.68 (0.61–0.75) | 0.57 (0.44–0.62) | 0.53 (0.46–0.61) |
| PPROM | 0.58 (0.50–0.65) | 0.67 (0.61–0.78) | 0.65 (0.58–0.72) | 0.66 (0.58–0.73) |
| Objective infection | 0.56 (0.49–0.63) | 0.62 (0.54–0.69) | 0.53 (0.46–0.60) | 0.53 (0.45–0.60) |
| Fetal adverse outcomes | 0.53 (0.45–0.60) | 0.56 (0.49–0.63) | 0.54 (0.47–0.61) | 0.40 (0.33–0.48) |
Values in bold are statistically significant at p < 0.05.