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. 2020 Jul 21;10:12092. doi: 10.1038/s41598-020-69000-3

Table 4.

Criterion values and coordinates of the ROC curve of serum IL-32 concentration for distinguishing COPD from healthy people.

Criterion Sensitivity 95% CI Specificity 95% CI  + LR 95% CI − LR 95% CI
> 53 100.00 96.9–100.0 12.86 6.1–23.0 1.15 0.6–2.1 0.00
> 63 99.14 95.3–100.0 15.71 8.1–26.4 1.18 0.7–2.0 0.055 0.008–0.4
> 87 96.55 91.4–99.1 37.14 25.9–49.5 1.54 1.1–2.1 0.093 0.03–0.2
> 90 89.66 82.6–94.5 41.43 29.8–53.8 1.53 1.2–2.0 0.25 0.1–0.4
> 94 88.79 81.6–93.9 48.57 36.4–60.8 1.73 1.3–2.2 0.23 0.1–0.4
> 101 87.93 80.6–93.2 58.57 46.2–70.2 2.12 1.7–2.6 0.21 0.1–0.4
> 105* 85.34 77.6–91.2 64.29 51.9–75.4 2.39 2.0–2.9 0.23 0.1–0.4
> 113 70.69 61.5–78.8 70.00 57.9–80.4 2.36 1.9–2.9 0.42 0.3–0.7
> 123 60.34 50.8–69.3 71.43 59.4–81.6 2.11 1.7–2.6 0.56 0.4–0.9
> 139 56.90 47.4–66.1 84.29 73.6–91.9 3.62 3.0–4.4 0.51 0.3–0.9
> 150 47.41 38.1–56.9 90.00 80.5–95.9 4.74 3.9–5.8 0.58 0.3–1.2
> 163 42.24 33.1–51.8 97.14 90.1–99.7 14.78 11.9–18.4 0.59 0.2–2.4
> 181 37.07 28.3–46.5 100.00 94.9–100.0 0.63

ROC receiver operating characteristic curve, IL-32 interleukin-32, COPD chronic obstructive pulmonary disease, 95% CI 95% confidence, +LR positive likelihood ratio, −LR negative likelihood ratio.