Figure 3.
Mitomycin C (MMC) preconditioning suppressed inflammatory gene expression in the allografted islets. The islets were subjected to mRNA extraction after a 24-h culture. Notably, MMM preconditioning suppressed the expression of interleukin (IL)-1beta, monocyte chemoattractant protein (MCP)-1, IL-6 and tumour necrosis factor (TNF)-α mRNA (p < 0.05, n = 4 for all). Hypoxanthine phosphoribosyltransferase (HPRT) mRNA was used as an internal control.