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. 2020 Jul 21;11:3652. doi: 10.1038/s41467-020-17433-9

Fig. 1. Global lipidomics of ZIKV-infected human cells.

Fig. 1

a Study overview. Huh7 cells were infected with ZIKV strain FSS13025 for 24 or 48 h. Each experimental condition (Mock 24 hpi, ZIKV 24 hpi, Mock 48 hpi, and ZIKV 48 hpi) had n = 5 replicates for a total of 20 biological samples, 19 of which were included in our final analysis. b Principal component analysis (PCA) of the lipidomics dataset. Colored arrows represent individual lipid species. c, d Bubble plots of log2 fold changes in abundance of lipid species in ZIKV-infected cells relative to mock at 24 hpi (c) and 48 hpi (d). Bubble size represents P value from one-way ANOVA or g test. See also Supplementary Fig. 1, Supplementary Data 1, and the Source Data file.