Table 2.
GO functional group analysis with their associated genes (data generated by ClueGO plugin).
| GOID | GO term | GO groups | Associated genes found |
|---|---|---|---|
| KEGG:04137 | Mitophagy | Group00 | [KRAS, RELA, SP1, SRC, TP53] |
| R-HSA:10906 | Intrinsic pathway for apoptosis | Group01 | [AKT1, CASP8, TP53] |
| KEGG:05167 | Kaposi's sarcoma-associated herpes virus infection | Group02 | [AKT1, CASP8, CCR5, CREB1, CREBBP, CXCL8, KRAS, MAPK1, NFKB1, RB1, RELA, SRC, STAT1, SYK, TP53] |
| KEGG:04210 | Apoptosis | Group03 | [AKT1, CASP8, KRAS, MAPK1, NFKB1, RELA, TP53] |
| KEGG:04926 | Relaxin signalling pathway | Group04 | [AKT1, CREB1, EDN1, KRAS, MAPK1, NFKB1, RELA, SRC] |
| KEGG:05161 | Hepatitis B | Group05 | [AKT1, CASP8, CREB1, CREBBP, CXCL8, KRAS, MAPK1, NFKB1, RB1, RELA, SRC, STAT1, TP53] |
| KEGG:05218 | Melanoma | Group06 | [AKT1, CDH1, KRAS, MAPK1, RB1, TP53] |
| KEGG:04919 | Thyroid hormone signalling pathway | Group07 | [AKT1, CREBBP, HDAC3, KRAS, MAPK1, SRC, STAT1, TP53] |
| R-HSA:8940973 | RUNX2 regulates osteoblast differentiation | Group08 | [HDAC3, MAPK1, RB1, SRC] |
| KEGG:05203 | Viral carcinogenesis | Group09 | [CASP8, CCR5, CREB1, CREBBP, HDAC3, KRAS, MAPK1, NFKB1, RB1, RELA, SRC, SYK, TP53] |
| KEGG:04066 | HIF-1 signalling pathway | Group10 | [AKT1, CREBBP, EDN1, MAPK1, NFKB1, RELA] |
| KEGG:05165 | Human papilloma virus infection | Group11 | [AKT1, ATR, CASP8, CREB1, CREBBP, HDAC3, KRAS, MAPK1, NFKB1, RB1, RELA, STAT1, TP53] |
| KEGG:05212 | Pancreatic cancer | Group12 | [AKT1, KRAS, MAPK1, NFKB1, RB1, RELA, STAT1, TP53] |
| R-HSA:8878166 | Transcriptional regulation by RUNX2 | Group13 | [AKT1, HDAC3, MAPK1, RB1, SRC, STAT1] |
| KEGG:05215 | Prostate cancer | Group14 | [AKT1, CREB1, CREBBP, KRAS, MAPK1, NFKB1, RB1, RELA, TP53] |
| KEGG:04062 | Chemokine signalling pathway | Group15 | [AKT1, CCR5, CXCL8, KRAS, MAPK1, NFKB1, RELA, SRC, STAT1] |
| KEGG:05152 | Tuberculosis | Group16 | [AKT1, CASP8, CREB1, CREBBP, MAPK1, NFKB1, RELA, SRC, STAT1, SYK] |