Table 1.

Demographic data, clinical characteristics and outcome in nine cases of Candida meningitis

Patient no.	Age/Sex	Brain disease	Neurosurgical history	History of other diseases	Glucocorticoid	Antecedent infection	Antibiotics	Species	Disseminated candidiasis	Albumin(g/L)	Haemoglobin(g/L)	Treatment	Antifungal agent	Outcome
1	48/M	Trauma	Haematoma clearance, VP, draining of subdural effusion	Hypertension	No	Pulmonary	Sulperazone	Candida parapsilosis, Candida famata	None	40.9	85	Shunt removement, external ventricular drainage, lumbar drainage	Fluconazole, Voriconazole	Survived
2	72/M	Glioma	Tumour resection	Hypertension	Yes	Brain	Ceftazidime, vancomycin	Candida parapsilosis	None	34	126	Lumbar drainage	Fluconazole	Survived
3	7/M	Trauma	Haematoma clearance, CSF leakage repair, external ventricular drainage, lumbar drainage	None	NK	Brain, pulmonary	NK	Candida albicans, Candida famata	None	39.5	134	Lumbar puncture	Fluconazole	Survived
4	70/M	Trauma	Haematoma clearance, lumbar drainage	Hypertension	No	Brain, pulmonary	Linezolid, meropenem	Candida albicans	None	37.1	77	Lumbar drainage	Fluconazole,Voriconazole	Death
5	51/M	Trauma	Haematoma clearance, lumbar drainage	None	Yes	Brain, pulmonary	Linezolid, meropenem	Candida albicans	Pulmonary (Candida albicans, Candida glabrate)	36.3	79	Lumbar drainage, craniotomy for infection clearance and CSF leakage repair	Fluconazole	Survived
6	38/M	Trauma	Haematoma clearance, CSF leakage repair, lumbar drainage	None	Yes	Brain, pulmonary	Linezolid, meropenem, tigecycline	Candida albicans	None	37.2	60	Lumbar drainage	Fluconazole	Survived
7	67/M	Trauma	Haematoma clearance, VP	Hypertension	No	Brain, pulmonary	Linezolid, meropenem,	Candida parapsilosis	Pulmonary (Candida albicans)	35.6	87	Shunt removement, lumbar drainage	Fluconazole, Voriconazole	Survived
8	46/F	Trauma	Haematoma clearance, LP	Diabetes	No	Brain, pulmonary, urinary	Meropenem, ciprofloxacin	Candida albicans	None	38.3	143	Shunt removement, external ventricular drainage, lumbar drainage	Fluconazole	Survived
9	73/M	Heamorrhage	Haematoma clearance, debridement, external ventricular drainage	Hypertension	No	Brain, pulmonary	Linezolid, meropenem,	Candida glabrata	None	32.7	86	Lumbar drainage	Voriconazole	Survived

NK, not known.