Table 2.
Size and location of oral mucosal biopsy used in COMET
| Studies | Biopsy size (mm2) | Location of biopsy |
|---|---|---|
| [13] | 2–3 | NA |
| [14] | 9 | Buccal mucosa |
| [15] | 2–3 | NA |
| [16] | 3–5 | NA |
| [17] | 2–3 | NA |
| [18] | NA | NA |
| [19] | 50.24a | Buccal mucosa (inferior) |
| [20] | 36 | NA |
| [21] | 36 | Buccal mucosa |
| [22] | 8 | Buccal mucosa |
| [23] | 50.24a | Buccal mucosa (inferior) |
| [24] | NA | NA |
| [25] | NAc | NA |
| [26] | 9 | Buccal mucosa (cheek) |
| [27] | 50.24a | Inferior buccal mucosa |
| [28] | 36 | Buccal mucosa |
| [29] | 9.42b | Buccal mucosa |
| [30] | 9.42b | Buccal mucosa |
| [31] | 4.71c | Buccal mucosa (cheek, 20 mm behind the angle of the mouth) |
| [32] | 3–5 | Buccal mucosa (inferior) |
| [33] | 100 | Buccal mucosa |
| [34] | NA | Labial mucosa (behind the lip) |
| [35] | 120–200 | Labial mucosa (inside the inferior lip) |
| [36] | 16 | Buccal mucosa (cheek) |
NA not available
Area of an a8-, b6-, or c3-mm diameter biopsy punch