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. 2020 Jul 22;11:311. doi: 10.1186/s13287-020-01826-0

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — The effect of mMSCs overexpressing TGFβ1 on the permeability of LPS-induced lungs in mice. a Lung oedema was analysed by LWW/BW (n = 3, *p < 0.05 compared with the control group; ^#p < 0.05 compared with the ARDS group). b Total protein and c albumin concentrations in bronchoalveolar lavage fluid were analysed by a mouse-specific ELISA kit to evaluate the permeability of the lung (n = 3, *p < 0.05 compared with the control group; ^#p < 0.05 compared with the ARDS group; ^δp < 0.05 compared with the LPS + mBM-MSC-NC group). d Expression of the occludin protein in the lungs of all the experimental groups at 3 and 7 days after mMSCs administration was evaluated by western blot analysis (n = 3, *p < 0.05 compared with the control group; ^#p < 0.05 compared with the ARDS group; ^δp < 0.05 compared with the LPS + mBM-MSC-NC group). ALB, albumin; ARDS, acute respiratory distress syndrome; ELISA, enzyme-linked immunosorbent assay; LWW/BW, lung wet weight/body weight; mMSCs, mouse mesenchymal stem cells; NC, normal control; TP, total protein