Table 1.
The numbers of the patients with eight representative epi-IDs and affected DMRs
| epi-IDs | Affected DMRs | n |
|---|---|---|
| Silver-Russell syndrome | H19/IGF2:IG-DMR hypomethylation | 77 |
| Beckwith-Wiedemann syndrome | H19/IGF2:IG-DMR hypermethylation | 9 |
| KCNQ1OT1:TSS-DMR hypomethylation | 22 | |
| Kagami-Ogata syndrome | MEG3/DLK1:IG-DMR and MEG3:TSS-DMR hypermethylation | 5 |
| Temple syndrome | MEG3/DLK1:IG-DMR and MEG3:TSS-DMR hypomethylation | 4 |
| Prader-Willi syndrome | SNURF:TSS-DMR hypermethylation | 4 |
| Angelman syndrome | SNURF:TSS-DMR hypomethylation | 5 |
| Pseudohypoparathyroidism 1B | GNAS A/B:TSS-DMR hypomethylation | 8 |
| Transient neonatal diabetes mellitus | PLAGL1:alt-TSS-DMR hypomethylation | 2 |
| Total | 136 |
epi-IDs epimutation-mediated imprinting disorders, DMRs differentially methylated regions