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. 2020 Jul 21;18:91. doi: 10.1186/s12915-020-00819-y

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — ADCC to gp120-coated and ADA-infected target cells. a RFADCC using gp120-coated GFP-CEM-NKR-CCR5-SNAP target cells over a range of antibody concentrations (0.0003–10 μg/ml) displayed as % killing. n = 3, mean ± SEM. Anti-Cluster A antibody C11 and palivizumab were used as positive and negative controls, respectively. b Heat map showing the ADCC activity measures as area under the curve (AUC), maximum lysis and EC50 for all five CoRBS antibodies in the RFADCC assay. c ADCC against pNL4/ADA and pNL43/ADA/N-U- infected CEM-NKR target cells over a range of antibody concentrations. N = 3, mean + SEM, individual data is displayed in Additional files 7 and 8