Skip to main content
. 2020 May 30;10(7):e01675. doi: 10.1002/brb3.1675

FIGURE 2.

FIGURE 2

BMSC transplantation conferred protection against tissue loss and long‐term motor deficits due to controlled cortical impact (CCI) injury. (a) The groups transplanted with BMSCs exhibited significantly less tissue loss (cavity size) produced by CCI trauma 35 days after TBI than did the control group. (b) Quantitation of the differences in the lesion volumes 35 days postinjury between the BMSC‐treated and untreated mice (n = 8). (c) The wire‐hanging test: BMSC treatment attenuated motor deficits leading to higher performance scores than those in the control group for as many as 35 days postinjury (n = 4). (d) Grid test: The administration of BMSCs also diminished biased forelimb use for as many as 4 weeks postinjury (n = 8). (e) Cylinder test: The administration of BMSCs also diminished biased forelimb use for as many as 35 days postinjury (n = 4). Data are all presented as the mean ± SD. *p < .05, **p < .01