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Septal coronary relaxation induced by acetylcholine in imeglimin‐treated Zucker fa/fa rats (filled triangles) either 1 h after single administration (left), and after 9 (center) as well as 90‐d treatment (right), and in age‐matched untreated Zucker fa/fa rats (filled circles). Twenty‐four wk‐old untreated Zucker fa/+ (open circles) were used as healthy control *: P<.05 vs Zucker fa/+ rats; †: P<.05 vs untreated Zucker fa/fa
