FIGURE 8.

Inhibition of SIRT1 can block the BDMC‐mediated improvements in learning, memory in APP/PS1 mice. Data are expressed as the mean ± SD from 5 to 7 mice per group. (a) The correct replacement rate of the mice was measured with a Y maze. (b) The escape latent period of the mice was tested with Morris water maze. (c) The mice were assayed for the number of through the escape platform region. (d) The mice were assayed for time spent in target quadrant. (e) The mice were assayed for swimming speed in Morris water maze. ^* p < .001 versus APP/PS1 mice