. Author manuscript; available in PMC: 2020 Sep 1.

Published in final edited form as: Ophthalmol Glaucoma. 2019 May 29;2(5):319–326. doi: 10.1016/j.ogla.2019.05.003

Table 4.

Annual Cumulative Proportion Estimates (95% Confidence Interval) of ≥5 μm Gain in Retinal Nerve Fiber Layer on Spectral-Domain Optical Coherence Tomography in Glaucoma and Control Cohorts by Flexible Parametric Models.

Rule of 5: ≥5 μm Gains	Year 2	Year 3	Year 4	Year 5	Year 6
Glaucoma	0.077 (0.053 – 0.111)	0.159 (0.123 – 0.204)	0.216 (0.173 – 0.267)	0.274 (0.227– 0.329)	0.371 (0.317 – 0.430)
Controls	0.013 (0.003 – 0.051)	0.040 (0.016 – 0.094)	0.096 (0.050 – 0.181)	0.198 (0.125 – 0.307)	0.350 (0.242 – 0.488)