Pregravid BMI: 25–35 kg/m2 Planning a subsequent pregnancy within the next 24 months Previous full-term singleton pregnancy (gestational age > 37 weeks) 18–40 years at time of enrollment Vaginal or cesarean delivery Normal glucose tolerance or GDM, but without evidence of postpartum diabetes Normal blood pressure or mild preeclampsia but normal postpartum blood pressure Bottle or breast feeding Normal thyroid function, normal blood cell count, normal kidney function and normal liver function. Lipid profile with triglyceride levels not higher than 400 mg/dL (fasting) and LDL levels less than 180 mg/dL. No clinical signs or symptoms of CVD or any other disease or condition that may contraindicate participation in exercise training (i.e. COPD, severe asthma, orthopedic abnormalities) Using contraception |
Pre- or post-delivery diabetes Post-delivery hypertension requiring medication Asthma requiring more than occasional use of sympathomimetic inhaler, but not chronic inhaled steroids Inflammatory Bowel Disease Need for assisted reproductive technologies to become pregnant Medical or obstetrical contraindication to the defined exercise or diet program Tobacco, excessive alcohol use (greater than 2 drinks/day) or illicit drug use Eating disorders such as bulimia Gastric surgery to lose weight including banding or bypass procedures Any psychological or psychiatric condition which may impair participation in lifestyle intervention HIV, or hepatitis B or C based on patient’s history More than two live births If a LIPP participant becomes pregnant prior to 16 weeks after randomization before the weight-loss phase for the lifestyle intervention is completed or a control subject becomes pregnant before the 3-month postpartum randomization, i.e. no baseline measurement Congenital heart disease unless accompanied by a letter from the participant’s cardiologist clearing exercise participation |
