Figure 1.

Schematic diagram of the engineered biofilms for disinfecting viruses from water. Genetically engineered E. coli biofilms specifically bind with and thus disinfect water transmission influenza virus from river water through functional extracellular amyloid nanofibers comprising CsgA‐C5 monomers. The C5 peptide, previously identified by phage display,^{[ 21 ]} was rationally fused with the CsgA protein to form CsgA‐C5 fusion monomer. CsgA‐C5 proteins can be secreted out of the bacteria cells and self‐assemble into the amyloid fibers comprising the extracellular matrix of engineered biofilms.