Table 1.
Baseline Characteristics | All participants (N=1212) |
No all- cause hospitalizations (N=480) |
1 all- cause hospitalization (N=242) |
2 or more all- cause hospitalizations (N=490) |
P value |
---|---|---|---|---|---|
Age (years) | 59.7 (53.6, 67.2) | 57.4 (52.8, 65.0) | 60.6 (53.9, 67.9) | 61.1 (54.4, 68.8) | <.0001 |
Male | 1064(87.8%) | 429(89.4%) | 213(88.0%) | 422(86.1%) | 0.1219 |
Minority | 421(34.7%) | 252(52.5%) | 64(26.4%) | 105(21.4%) | <.0001 |
BMI (kg/m2) | 26.8 (24.0, 29.8) | 26.1 (23.6, 29.4) | 26.7 (24.1, 30.0) | 27.5 (24.4, 30.2) | 0.0002 |
Hypertension | 728(60.1%) | 286(59.6%) | 143(59.1%) | 299(61.0%) | 0.6467 |
Hyperlipidemia | 730(60.3%) | 254(52.9%) | 147(60.7%) | 329(67.4%) | <.0001 |
Diabetes | 478(39.4%) | 156(32.5%) | 93(38.4%) | 229(46.7%) | <.0001 |
Previous stroke | 92(7.6%) | 31(6.5%) | 19(7.9%) | 42(8.6%) | 0.2146 |
Peripheral vascular disease | 184(15.2%) | 68(14.2%) | 28(11.6%) | 88(18.0%) | 0.0983 |
Chronic renal insufficiency | 94(7.8%) | 27(5.6%) | 14(5.8%) | 53(10.8%) | 0.0024 |
Atrial fibrillation/flutter | 153(12.6%) | 57(11.9%) | 28(11.6%) | 68(13.9%) | 0.3467 |
Previous PCI | 156(12.9%) | 37(7.7%) | 33(13.6%) | 86(17.6%) | <.0001 |
Previous CABG | 36(3.0%) | 17(3.5%) | 5(2.1%) | 14(2.9%) | 0.5331 |
Current NYHA | 0.6166 | ||||
I | 139(11.5%) | 49(10.2%) | 28(11.6%) | 62(12.7%) | |
II | 626(51.7%) | 250(52.1%) | 128(52.9%) | 248(50.6%) | |
III | 412(34.0%) | 170(35.4%) | 76(31.4%) | 166(33.9%) | |
IV | 35(2.9%) | 11(2.3%) | 10(4.1%) | 14(2.9%) | |
Heart rate (bpm) | 74.0 (66.0, 82.0) | 76.0 (69.0, 84.0) | 72.0 (64.0, 80.0) | 72.0 (64.0, 80.0) | <.0001 |
Systolic BP, (mmHg) | 120.0 (110.0, 130.0) | 120.0 (110.0, 130.0) | 120.0 (110.0, 130.0) | 120.0 (110.0, 130.0) | 0.0294 |
Diastolic BP, (mmHg) | 78.0 (70.0, 80.0) | 80.0 (70.0, 80.0) | 76.5 (70.0, 80.0) | 75.0 (68.0, 80.0) | <.0001 |
Plasma hemoglobin (g/dL) | 13.9 (12.7, 14.9) | 14.0 (12.9, 15.0) | 13.8 (12.6, 14.8) | 13.8 (12.4, 14.8) | 0.0082 |
Baseline EF (%) | 28.0 (22.0, 34.0) | 28.0 (23.0, 34.0) | 28.0 (22.8, 34.0) | 27.5 (22.0, 33.3) | 0.5038 |
Minority- Any patient whose ethnicity is Hispanic or Latino, or whose race is non-white. Continuous variables expressed as median and 25% - 75% interquartile range; MED- Randomized to best medical therapy; CABG- Randomized to coronary artery bypass surgery plus best medical therapy; kg- kilogram; NHYA- New York Heart Association; bpm- beats per minute; BMI- body mass index; BP- blood pressure; PCI- percutaneous coronary intervention; CABG- coronary artery bypass surgery; ESLVI- end systolic left ventricular volume index; EDVI- end diastolic left ventricular volume index. LAD- Left anterior descending artery.