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a) Schematic representation of CNC preparation from plant cellulose by selective acid hydrolysis of amorphous regions. b) AFM image of as-hydrolyzed CNC with residual sulfate ester groups. c) CNC activation with 1,1′-carbonyldiimidazole (CDI) followed by conjugation of amine-functionalized radiometal chelators p-NH2-Bn-NOTA (for copper-64), desferrioxamine B (DFO, for zirconium-89), and the Cyanine5 (Cy5) fluorophore.
